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  • Center of Biomedical Research Excellence (COBRE) for Skeletal Health and Repair

  • Qian Chen, Ph.D

    Joint diseases impact the quality of life of forty-six million Americans and are among the leading causes of disability in this country. When you also consider the aging "baby boomer" generation and soaring obesity rates, significant increases in the incidence of joint diseases can be expected in the decades to come.

    The COBRE for Skeletal Health and Repair in the Rhode Island Hospital enables clinicians and basic scientists, engineers and biologists to work side-by-side on multidisciplinary research, helping us to better understand cartilage and joint health mechanisms and develop strategies for the prevention and treatment of skeletal joint diseases.

    The COBRE award helps us to achieve three goals. First, we are expanding and renovating laboratory space and establishing research cores. Second, we are mentoring junior investigators, the majority of whom are clinicians/scientists treating patients every day. Third, we are conducting translational research ranging from preventing childhood limb deformities to treating adult bone cancer; from treating trauma or sports-injury induced arthritis to rebuilding a healthy joint using tissue engineering.

    On behalf of all the researchers here, I would like to thank the National Center for Research Resources of the National Institutes of Health for this award and for recognizing the great potential that exists in the field of skeletal research, particularly in the area of cartilage and joint health.

    I am honored to lead this COBRE center and hope the research performed at Rhode Island Hospital, in the Warren Alpert Medical School of Brown University and in the city of Providence will translate into newer and better treatments, cures, and preventive techniques that will improve the health of all Americans.

    Qian Chen, Ph.D
    Director and Principal Investigator
    COBRE for Skeletal Health and Repair